Custom Peptides
Cayman Chemical GluCys ammonium salt 10mg
An intermediate in GSH synthesis; formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase; an essential component of phytochelatins
Cayman Chemical 5-DeoxyadenosIn 10mg
An adenosine analog; an intermediate in the degradation of S-adenosyl-L-methionine; has been used in the study of enzyme kinetics, including those of phosphomethylpyrimidine synthase, glutamate mutase, and 5’-methylthioadenosine phosphorylase
Cayman Chemical PhensuxImIde 10mg
An anticonvulsant; inhibits MES- and pentylenetetrazole-induced seizures in mice (ED50s = 112 and 50 mg/kg, respectively); induces proteinuria and hematuria in rats at 1.25 mmol/kg
Cayman Chemical AcetylharpagIde 10mg
An iridoid glycoside with diverse biological activities; reduces the proliferation of A431 cancer cells (IC50 = 310 µM); reduces the number of tumors per mouse and the percentage of mice with tumors in a mouse model of 4-nitroquinolin 1-oxide-induced carcinogenesis at 0.005% in the drinking water; decreases carrageenan-induced paw swelling in rats at 10 mg/kg; reduces blood glucose levels in a mouse model of alloxan-induced type I diabetes at 10 mg/kg
Cayman Chemical MacImorelInacetate 10mg
A growth hormone secretagogue and ghrelin receptor agonist; binds to GHS-R1a (IC50 = 123 nM for the human receptor); oral administration increases plasma growth hormone levels in dogs at 1 mg/kg; decreases gastric acid secretion in pylorus-ligated rats at 0.01 or 1 nmol/animal, i.c.v.; increases acute food intake and body weight in mice at 10 mg/kg; decreases the number and total duration of seizures in mice induced with dopamine D1 receptor kindling using SKF 81297
Cayman Chemical 5 NethylNIsopropylAmIlo 10mg
A potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and NHE5 with Ki values of 0.02, 0.5, 2.4, and 0.42 μM, respectively; less effectively inhibits NHE4 (IC50 ≥10 μM)
Cayman Chemical Lapachone 10mg
A quinone which inhibits topoisomerase I at 25 μM and transglutaminase (IC50 = 5 μM); reduced to β-lapachone hydroquinone by NQO1, generating ROS during its reversion to β-lapachone; sensitizes cancer cells to radiation, suppresses NF-κB activation, and drives apoptosis
Cayman Chemical tculta Blnco Nobltn 10mg
A flavonoid; reduces LPS- and IFN-γ-induced increases in iNOS protein levels and NO production in RAW 264.7 cells at 25, 50, and 100 µM; decreases proliferation of A549, B16/4A5, CCRF-HSB-2, and TGBC11TKB cancer cell lines (IC50s = 22, 18, 13, and 8.3 µM, respectively); reduces body weight, hepatic steatosis, and plasma LDL and HDL cholesterol levels in mice fed a high-fat, high-cholesterol diet at 0.3% w/w; inhibits increases in plasma glucose levels in an intraperitoneal glucose tolerance test in the same model
Cayman Chemical PromestrIen 10mg
A synthetic estrogen; reduces vaginal atrophy and decreases in endometrial and myometrial wall thickness in ovariectomized rats when applied as a topical gel
Cayman Chemical MoexIprIl-d5 10mg
An internal standard for the quantification of moexipril by GC- or LC-MS
Revvity Health Sciences Inc AlphaLISA Human LC3B Detection Kit, Standard
AlphaLISA Human LC3B Detection Kit, Standard
Cayman Chemical Desvaleryl Valsartn 10mg
A potential impurity found in commercial preparations of valsartan; a degradation product formed under acidic conditions
Cayman Chemical 17phenyl trInor PrstglndI 10mg
17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.{3318,1025} 17-phenyl trinor PGE2 is an EP1 and EP3 receptor agonist.1,2 It causes contraction of the guinea pig ileum at a concentration of 11 µM.{3318} It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.{1025} With an ED50 value of 350 UG/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.{1025}
Cayman Chemical PB22 NpentnoIc acId3carb 10mg
A potential metabolite of PB-22; intended for forensic and research purposes
Cayman Chemical Galoflavn 10mg
An LDH inhibitor (Kis = 5.46 and 15.06 µM, for the A and B isoforms, respectively) that prevents proliferation of many different cancer cells by blocking glycolysis and ATP production